2015年2月8日 星期日

鋁與阿茲海默症

.

說鋁會引發阿茲海默症,並沒有根據。


1.
美國阿茲海默症協會

Myth 4: Drinking out of aluminum cans or cooking in aluminum
pots and pans can lead to Alzheimer’s disease.

Reality:
During the 1960s and 1970s, aluminum emerged as a possible
suspect in Alzheimer’s. This suspicion led to concern about
 exposure to aluminum through everyday sources such as pots
 and pans, beverage cans, antacids and antiperspirants.

Since then, studies have failed to confirm any role for
aluminum in causing Alzheimer’s. Experts today focus on
other areas of research, and few believe that everyday
sources of aluminum pose any threat.

http://www.alz.org/alzheimers_disease_myths_about_alzheimers.asp


重點翻譯

迷思4:
鋁容器會導致阿茲海默症。

事實:
1960 1970 年代,鋁被懷疑可能導致阿茲海默症。
這項懷疑引發了人們對鋁材料的關注。

但是,從那時起,就沒有任何研究可以證實鋁會導致阿茲海默症。

今天,專家專注在其他範圍找病因,很少專家相信日常鋁的來源會造構成任何威脅。


===================================


2.
英國阿茲海默症協會

'There is no conclusive medical or scientific evidence
of a link between aluminium and Alzheimer's disease.
There have been three independent scientific enquiries
into the Camelford incident, none of which have found
a causal link with dementia.

Whilst this is a sad and tragic incident, it should not
 lead to wider panic. Aluminium is one of the most
abundant minerals in the world, and worldwide research
 has not found any evidence that exposure to everyday
levels of aluminium is a risk factor for Alzheimer's
disease.

The Alzheimer's Society offers help and support to
families affected by dementia throughout the country
 and we would be happy to offer advice to any families
 living in the Camelford area.

We still do not know what causes Alzheimer's disease,
and until this time the Alzheimer's Society supports
all research into potential causes and cures.'

http://www.alzheimers.org.uk/site/scripts/news_article.php?newsID=169


重點翻譯

沒有確鑿的醫學或科學證據,證明鋁與阿茲海默症有關聯。

鋁是世界上最豐富的礦物質之一,全世界都無法證實暴露於鋁日常水準是
阿茲海默症的危險因子。

我們仍然不知道是什麼原因導致阿茲海默症,本協會持續支持所有的病因研究
及治療方法。




英國阿茲海默症協會的另一篇


https://www.alzheimers.org.uk/about-dementia/risk-factors-and-prevention/metals-and-dementia


Aluminium

In 1965, researchers found that rabbits injected with an
extremely high dose of aluminium developed toxic tau tangles
 in their brains. This led to speculation that aluminium
 from cans, cookware, processed foods and even the water
 supply could be causing dementia. The ability of this
high dose aluminium to induce tau tangles, increase amyloid
 levels and contribute to the development of plaques has
been shown in laboratory experiments on animals.

Importantly, these results were only seen with extremely
high exposures that far exceed the levels that can enter
 the body through food or potentially through contact with
 aluminium cookware.

Since this study was reported, much research has been done
 on the relationship of aluminium and Alzheimer's disease.
 As yet no study or group of studies has been able to
confirm that aluminium is involved in the development
of Alzheimer's disease.

Aluminium is seen in the normal, healthy brain. It is
not clear how aluminium is getting into the brain from
 the blood. The levels currently seen in peoples brains
 hasn't been shown to be toxic but an ageing brain may
be less able to process the aluminium. Although aluminium
has been seen in amyloid plaques there is no solid evidence
 that aluminium is increased in the brains of people with
Alzheimer's disease. No convincing relationship between
amount of exposure or aluminium in the body and the
development of Alzheimer's disease has been established.

Aluminium in food and drink is in a form that is not easily
 absorbed in to the body. Hence the amount taken up is less
 than 1% of the amount present in food and drink. Most of
the aluminium taken into the body is cleaned out by the
kidneys. Studies on people with kidney problems have shown
increased amounts of aluminium in the brain, due to the
inability of the kidneys to pass it into the urine. Although
 toxic effects were seen on the brain in these people, none
 of these were related to Alzheimer's disease.

One large recent study did find a potential role for high
dose aluminium in drinking water in progressing Alzheimer's
disease for people who already have the disease.

However, multiple other small and large scale studies have
 failed to find a convincing causal association between
aluminium exposure in humans and Alzheimer's disease.


多項小規模、大規模研究,都未能找到人類鋁暴露與阿爾茨海默病之間
令人信服的因果關係。




3.
加拿大阿茲海默症協會

http://alzheimer.ca/en/Home/About-dementia/Alzheimer-s-disease/Risk-factors/Aluminum


Is there a connection between aluminum and the
development of dementia?

Aluminum has been studied for over 40 years as
 a substance that might be linked to dementia.
However, there have been many conflicting findings.

Some studies show increased levels of trace elements
 of aluminum in the brains of people with dementia,
while others do not.

Studies have not found an increased incidence of
dementia in people with occupational exposure to
 aluminum.

Tea is one of the few plants whose leaves accumulate
 larger trace element amounts of aluminum that can
seep into the brewed beverage. However, there is no
 evidence that dementia is more prevalent in cultures
 that typically drink large amounts of tea.

Unfortunately, earlier animal studies focused on one
 animal that is particularly susceptible to aluminum
 poisoning, which has led to incorrect conclusions
about the general effects of aluminum on the body.

What about pots and pans?

It would be difficult to significantly reduce
exposure to aluminum simply by avoiding the
use of aluminum cookware, foil, beverage cans
 and other products.

Use of aluminum in pots and pans only contributes
 to a very small percentage of the average person's
 intake of aluminum.

In summary

Current research provides no convincing evidence
that exposure to trace elements of aluminum is
connected to the development of dementia.

生活中,鋁無所不在,避開使用鋁鍋鋁罐並不能大量減少鋁暴露。

結論

目前的研究沒有令人信服的證據可以證明接觸微量鋁元素與阿茲海默症的發展有關。











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